In astronomy, the interstellar medium (ISM) is the matter and radiation that exist in the space between the star systems in a galaxy. This matter includes gas in ionic, atomic, and molecular form, as well as dust and cosmic rays. It fills interstellar space and blends smoothly into the surrounding intergalactic space. The energy that occupies the same volume, in the form of electromagnetic radiation, is the interstellar radiation field. The interstellar medium is composed of multiple phases distinguished by whether matter is ionic, atomic, or molecular, and the temperature and density of the matter. The interstellar medium is composed, primarily, of hydrogen, followed by helium with trace amounts of carbon, oxygen, and nitrogen comparatively to hydrogen. The thermal pressures of these phases are in rough equilibrium with one another. Magnetic fields and turbulent motions also provide pressure in the ISM, and are typically more important, dynamically, than the thermal pressure is. In all phases, the interstellar medium is extremely tenuous by terrestrial standards. In cool, dense regions of the ISM, matter is primarily in molecular form, and reaches number densities of 106 molecules per cm3 (1 million molecules per cm3). In hot, diffuse regions of the ISM, matter is primarily ionized, and the density may be as low as 10−4 ions per cm3. Compare this with a number density of roughly 1019 molecules per cm3 for air at sea level, and 1010 molecules per cm3 (10 billion molecules per cm3) for a laboratory high-vacuum chamber. By mass, 99% of the ISM is gas in any form, and 1% is dust. Of the gas in the ISM, by number 91% of atoms are hydrogen and 8.9% are helium, with 0.1% being atoms of elements heavier than hydrogen or helium, known as "metals" in astronomical parlance. By mass this amounts to 70% hydrogen, 28% helium, and 1.5% heavier elements. The hydrogen and helium are primarily a result of primordial nucleosynthesis, while the heavier elements in the ISM are mostly a result of enrichment in the process of stellar evolution. The ISM plays a crucial role in astrophysics precisely because of its intermediate role between stellar and galactic scales. Stars form within the densest regions of the ISM, which ultimately contributes to molecular clouds and replenishes the ISM with matter and energy through planetary nebulae, stellar winds, and supernovae. This interplay between stars and the ISM helps determine the rate at which a galaxy depletes its gaseous content, and therefore its lifespan of active star formation. Voyager 1 reached the ISM on August 25, 2012, making it the first artificial object from Earth to do so. Interstellar plasma and dust will be studied until the estimated mission end date of 2025. Its twin Voyager 2 entered the ISM on November 5, 2018.